In Your 40s

Now is the time to turn your awareness of good health into ACTION.

These are guidelines only. Your healthcare provider will personalize the timing of each test to meet your specific healthcare needs.


General health

  • Full checkup — Including weight and height.
  • Sleep habits — Discuss at your annual exam.
  • Thyroid (TSH) test —Discuss with your healthcare provider.
  • HIV screening — Get this test if you are at risk for HIV infection (unprotected sex, sexually transmitted disease, or used drugs with needles).
  • Hepatitis C (HCV) screening — Get this one-time screening if you were born between 1945 and 1965.

Heart health

  • Blood pressure test — At least every two years.
  • Cholesterol panel — Total, LDL, HDL and triglycerides; discuss with your healthcare provider.

Bone health

  • Bone density screen —Discuss with your healthcare provider.


  • Blood glucose or A1c test — Get screened if you have sustained blood pressure greater than 135/80, take medicine for high blood pressure, or are at risk for developing diabetes.

Breast health

  • Breast awareness —Know how your breasts normally look and feel so you can report any changes to your healthcare provider.
  • Clinical breast exam —Yearly.
  • Mammogram — Yearly, starting at the age of 40. (Possibly earlier if high risk or family history of breast cancer; discuss with your healthcare provider)

Reproductive health

  • Pap test — At least every three years.
  • Pelvic exam — Yearly.
  • Sexually transmitted infection (STI) tests —Both partners should get tested for STIs, including HIV, before initiating sexual intercourse. Get a chlamydia test if you have new or multiple partners.

Mental health screening

  • Discuss with your healthcare provider.

Eye and ear health

  • Comprehensive eye exam — Baseline exam at age 40, then every 2-4 years as your healthcare provider advises.
  • Hearing test — Every 10 years.

Skin health

  • Skin exam — Monthly self-exam of skin and moles and as part of a routine full checkup with your healthcare provider.

Oral health

  • Dental cleaning and exam — Discuss with your dentist the right frequency for you.


  • Seasonal influenza vaccine — Yearly.
  • Tetanusdiphtheria- pertussis booster vaccine — Every 10 years.

Sources: U.S. Department of Health and Human Services Office on Women’s Health, Centers for Disease Control and Prevention

Spirit_of_Women_Decade_Cards_40s (PDF)